HPLC Columns - Nucleosil

MACHEREY-NAGEL, the manufacturer of NUCLEOSIL^® HPLC phases and one of the leading companies for chromatography products, presents its Reversed Phase Application Guide.

The 160-page publication includes an introduction to the theoretical aspects of HPLC, a lot of information about modern stationary phases, retention, selectivity and mobile phases.

Aside 150 up-to-date and relevant applications the special chapters Do's and Don'ts and trouble-shooting provide a lot of helpful hints and tips for a successful chromatography. A special section explains basic aspects and demands of preparative HPLC.

The applications are divided in the fields of:

• Drugs
• Biological and natural compounds
• Food analysis
• Environmental analysis
• Organic compounds

Several different surface modifications based on NUCLEODUR^® silica have been developed over the last years providing a full range of specified HPLC phases and an ideal tool for every separation:

• NUCLEODUR^® C18 Gravity and C8 Gravity
• NUCLEODUR^® C18 Isis
• NUCLEODUR^® C18 Pyramid
• NUCLEODUR^® PolarTec
• NUCLEODUR^® PFP
• NUCLEODUR^® Sphinx RP
• NUCLEODUR^® C18 HTec
• NUCLEODUR^® C18 ec and C8 ec
• NUCLEODUR^® HILIC
• NUCLEODUR^® CN and CN-RP
• NUCLEODUR^® NH2 and NH2-RP
• unmodified NUCLEODUR^®

Ultrafast separations beyond high pressure driven UHPLC Core-shell silica

NUCLEOSHELL^® core-shell particle technology from MACHEREY-NAGEL is an alternate route to gain highest column efficiency and resolution at almost the same short run time but with much lower back pressure.

NUCLEOSHELL^® modifications

The program of NUCLEOSHELL^® surface modifications now comprises the following phases:

• NUCLEOSHELL^® RP 18
• NUCLEOSHELL^® RP 18plus NEW!
• NUCLEOSHELL^® Phenyl-Hexyl
• NUCLEOSHELL^® PFP
• NUCLEOSHELL^® HILIC