COSMOSIL 5C18-MS-II is a monomeric type of C18 phase. A new end capping treatment with polar groups of “sheild eect” has extended the pH range and signicantly improved peak shape for basic compounds. This phase is recommended for most of application but particularly eective for low molecular weight organic compounds.
COSMOSIL 5C18-AR-II is a polymeric type of C18 phase. It shows exceptional stability and long lifetime at low pH. This phase is recommended for the separations requiring acidic mobile phase conditions. It also shows superior molecular shape selectivity to monomeric type C18 columns
COSMOSIL 5C18-PAQ is designed to oer superior retention of polar compounds and excellent reproducibility in highly aqueous mobile phases, even in 100% aqueous
Conventionally aminopropyl bonded stationary phases are used for liquid chromatographic analysis of mono and oligosaccharides. General shortcomings of the conventional aminopropyl bonded phases are tailing and adsorption of certain saccharides and general low durability (short active life) of these columns. These problems are addressed and solved by the novel COSMOSIL Sugar-D, resulting in better (sharper) separation and much improved durability.
In addition COSMOSIL Sugar-D is useful at the separation of highly hydrophilic compounds which are not retained in conventional octadecyl (ODS) bonded statinoary phases.
COSMOSIL Protein-R is a reversed phase HPLC column designed specically for protein and peptide separation. COSMOSIL C Protein-R provides signicantly improved peak shapes, high recovery rate and outstanding stability at low pH, which are often problematic for the separation of proteins and peptides with conventional C18-300 A and C4-300 A columns.
Ultra-pure silica gel of more than 99.99% purity is used for the COSMOSIL SL-II packed column series. This column provides improved separation and reproducibility for compounds with carbonyl or phenol hydroxyl groups, which are often problematic to separate using conventional silica gel columns because of interference of metallic impurities. The follwoings are applications of COSMOSIL SL-II column on organic acids, acid amides and phenols. COSMOSIL SL-II provides improved separation for these compounds without ionic addtives by using mobile phases of hexane and ethanol.
COSMOSIL 3.0 mm I.D. columns were developed aiming at high sensitivity and the reduction of solvent requirement. A 3.0 mm I.D. column is about twice as sensitive as a 4.6 mm I.D. column. High performance packing material of the same COSMOSIL series is filled into the 3.0 mm 1.D. column. As a result, high reproducibility is achieved for separation of chelating compounds and basic compounds. In addition, there is no change the HPLC system. This is a significant advantage over semi-micro bore columns. By using a mid-core 3.0 mm I.D. column, high sensitivity and economical solventconsumption can be achieved on anyconventional HPLC systems
COSMOSIL CNT series are ideal for separation of soluble carbon nanotubes based on sizes. COSMOSIL CNT series are packed with hydrophilic group-bonded silica packing material. The columns are specially designed to avoid adsorption of carbon nanotubes to silica support and thus ensure high resolution and maximum recovery of carbon naotubes. COSMOSIL CNT series are available in three different sizes, 300 A, 1000 A and 2000 A, respectively.