What is Gas Liquid Chromatography ?
- Gas-liquid chromatography (GLC), also known as gas chromatography (GC), is a technique used in analytical chemistry for separating and analyzing compounds that can be vaporized without decomposition. In GLC, a mixture of compounds is vaporized and then injected into the head of a chromatographic column.
- The column is typically coated with a stationary phase, which interacts differently with each compound in the mixture. As the vaporized compounds travel through the column, they are separated based on their differing interactions with the stationary phase.
- A carrier gas, such as helium or nitrogen, is used to push the vaporized compounds through the column. The separated compounds then exit the column and are detected by a detector, such as a flame ionization detector or a mass spectrometer.
- GLC is widely used in various fields including environmental analysis, pharmaceuticals, food and beverage analysis, and forensics due to its high resolution, sensitivity, and ability to separate a wide range of compounds.